Sam Darnold spent last season as the backup quarterback in San Francisco, so 49ers head coach Kyle Shanahan is familiar with ...

San Francisco 49ers head coach Kyle Shanahan believes Deebo Samuel would be a stellar running back in the NFL.

Christian McCaffrey's calf and Achilles injuries continues to linger as the team considers placing him on injured reserve.

Detroit Lions head coach Dan Campbell and his wife Holly are selling their home due to security concerns after their address ...

Saleh is now in his fourth year as the head coach of the Jets and has yet to lead the team to the postseason. He has also ...

Although the famed Rams-49ers rivalry has been decidedly tilted in San Francisco’s direction in recent years, the games have ...

The retirement of Aaron Donald has shifted the landscape, pushing both the 49ers and Rams to adapt their strategies for an ...

Looking at Sunday’s San Francisco 49ers at LA Rams Week 3 NFL odds, lines and trends. Here’s what you need to know.

The Los Angeles Rams host the San Francisco 49ers on Sunday as both NFC West rivals try to shake off dismal Week 2 ...

San Francisco 49ers head coach Kyle Shanahan has one less problem to worry about when facing division rival, the Los Angeles ...

Detroit Lions head coach Dan Campbell is selling his house in Bloomfield Hills, Michigan after the address leaked online.

The San Francisco 49ers have provided new injury updates ahead of Thursday's practice, adding two more key players to the list of those sidelined alongside wide receiver Deebo Samuel (calf strain) and ...