NFL teams grapple with mounting injuries, forcing them to rely on backups and adapt strategies as the season progresses.

An oblique injury has kept Seattle Seahawks running back Kenneth Walker III out of the lineup. He missed their Week 2 win ...

According to Tallysight, a whopping 96% of experts are picking the 49ers to beat the Rams. It’s slightly better when ...

Week 3 matchup vs. Rams with key injuries to McCaffrey, Samuel, and Kittle, testing their depth in this crucial NFC West ...

Purdy still hasn't entirely shaken the "system" quarterback label and other denigrations. A chance for his rebuttal is now ...

The San Francisco 49ers face the Los Angeles Rams in their first divisional matchup. The 49ers are coming off a loss to the ...

SportsLine's model reveals its Week 3 Fantasy football projections, PPR rankings, start-sit advice for sites like CBS Sports, ESPN and Yahoo ...

Purdy still hasn't entirely shaken the "system" quarterback label and other denigrations. A chance for his rebuttal is now ...

The 49ers are without Christian McCaffrey, Deebo Samuel and maybe George Kittle, while the Rams won’t have top receivers ...

Brock Purdy, The San Francisco Offense ... the prop lines for George Kittle and Brandon Aiyuk, especially with the Rams ...

The San Francisco 49ers could be without another key offensive player this week after All-Pro tight end George Kittle missed ...